Prof Dr Ertuğrul Göksoy

To present our 20 years experience of tuberculosis of the breast. Retrospective study. Teaching hospital, Turkey. 9 women with tuberculous mastitis. Cure. All cases underwent frozen section and excision. One required a simple mastectomy more

To present our 20 years experience of tuberculosis of the breast. Retrospective study. Teaching hospital, Turkey. 9 women with tuberculous mastitis. Cure. All cases underwent frozen section and excision. One required a simple mastectomy because of the extent of destruction; the remainder underwent lumpectomy. All patients were given rifampicin, ethambutol, and isoniazid, and the three who had tuberculosis of other organs were also treated with streptomycin. Mean follow up was 87 months (range ) and two patients were lost to follow up, at three and six years, respectively. Histological examination showed the presence of tubercle and central caseation in 8 cases and granulomatous infiltration in one. Tuberculous mastitis is rare, and should be suspected in any woman with persistent breast abscesses and sinuses, particularly if she lives in an area from which tuberculosis has not been eradicated. Conservative surgery and antituberculous drugs are the treatment of choice.

Background: The patient’s position is important for ensuring patient comfort and preventing complications after thyroidectomy. Objectives: This study was carried out to determine the effects of different degrees of head-of-bed elevation more

Background: The patient’s position is important for ensuring patient comfort and preventing complications after thyroidectomy. Objectives: This study was carried out to determine the effects of different degrees of head-of-bed elevation (HOBE) on the respiratory pattern and drainage following thyroidectomy and to provide suggestions for evidence-based clinical practice. Methods: The sample of this prospective, parallel arm, randomized controlled trial included patients undergoing thyroidec- tomy in a university hospital in Turkey. The patients were randomly assigned () to supine 0° (baseline), 30° and 45° HOBE groups. Respiratory pattern including respiratory rate (RR), peripheral oxygen saturation (SpO2) and dyspnea, and drainage including amount of drainage and hematoma formation were evaluated at the 1st, 2nd, 3rd and 4th hours following thy- roidectomy. Results: The majority of the patients (%) were female and % had undergone total thyroidectomy. The mean RR (

Rudolf Nissen, der ehemalige Direktor unserer Klinik, wurde am in Neisse geboren. Sein Medizinstudium wurde wegen des ersten Weltkrieges unterbrochen. Nissen wurde als Feldhilfsarzt an der Front vor Aufgaben gestellt und hier more

Rudolf Nissen, der ehemalige Direktor unserer Klinik, wurde am in Neisse geboren. Sein Medizinstudium wurde wegen des ersten Weltkrieges unterbrochen. Nissen wurde als Feldhilfsarzt an der Front vor Aufgaben gestellt und hier verletzt. Er bekam zwei Kugeln in die Lunge. Ab hat er mit seinem Studium in Breslau weitergemacht. Nach dem Studium erlangte er im Jahre seine Habilitation. Er arbeitete in der Charite Klinik in Berlin bei Prof. Sauerbruch und wurde zu jener Zeit zum jungsten Professor in Deutschland ernannt. Wahrend der dunklen Epoche der nationalsozialistischen Herrschaft emigrierten Professor Nissen — durch Empfehlung von Prof. Sauerbruch — und weitere Wissenschaftler, in die damals noch junge Turkische Republik. Mit 37 Jahren wurde Nissen als Ord. Professor zum Direktor der ersten Chirurgischen Klinik (jetzige Cerrahpasa) der Medizinischen Fakultat der Universitat Istanbul ernannt. muste er wegen eines Lungenabszesses infolge der Kriegsverletzung in die Vereinigten Staaten verreisen, um sich einer Therapie zu unterziehen. Inzwischen fing der zweite Weltkrieg an und er konnte nicht zuruckkommen. Die weiteren Stationen waren Boston, New York und endlich die Basler Klinik. Im Januar , mit 81 Jahren, starb er.

TEfiEKKUR Kuruluflundan bu yana, yillarinda Dergi Editoru ve Yay›n Kurulu Uyesi olarak gorev alm›fl Hocalar›m›za, Tum O¤retim Uyelerine teflekkur ederiz. Aram›zdan ayr›lanlar› sayg› ve minnetle an›yoruz. Onceki Editorler: Selcuk more

TEfiEKKUR Kuruluflundan bu yana, yillarinda Dergi Editoru ve Yay›n Kurulu Uyesi olarak gorev alm›fl Hocalar›m›za, Tum O¤retim Uyelerine teflekkur ederiz. Aram›zdan ayr›lanlar› sayg› ve minnetle an›yoruz. Onceki Editorler: Selcuk AYBAR (), Altan ONAT (), Bulent BERKARDA (), Vural SOLOK (), Yalc›n TUZUN ( ), seafoodplus.info SEYMEN - seafoodplus.info EROZENC‹ (). Yay›n Kurulu Uyeleri (Soyad›na gore): Gokhan AKKAN, Nuran AKMAN, Sevil ATASOY, Selcuk AYBAR, Talia Bali AYKAN, Nazif BA⁄RIACIK, Ayd›n BARLAS, Ifl›k BAfiAR, Bulent BERKARDA, Fikret B‹YAL, Nur DAN‹fiMEND, U¤ur DERMAN, Sabri ERGUNEY, Muzeyyen ERK, seafoodplus.info EROZENC‹, Vedat HAMURYUDAN, H. Husrev HATEM‹, Hurol ‹NSEL, Altan ONAT, Erdo¤an OZDAMAR, Huri OZDO⁄AN, Ali PUSANE, Haluk SANER, seafoodplus.info SEYMEN, Vural SOLOK, Mustafa fiENOCAK, Nukhet TUZUN, Yalc›n TUZUN, Orhan ULUT‹N, Ekrem Kadri UNAT, Nurhayat YILDIRIM. X

Üniversite Reformu, Atatürk’ün gösterdiği hedefler doğrultusundaki Türkiye Cumhuriyeti’nin gelişmelerinden biridir. Nazilerin yürürlüğe koyduğu kısıtlayıcı yasalar nedeniyle Almanya’da artık çalışma olanağı kalmayan bilim more

Üniversite Reformu, Atatürk’ün gösterdiği hedefler doğrultusundaki Türkiye Cumhuriyeti’nin gelişmelerinden biridir. Nazilerin yürürlüğe koyduğu kısıtlayıcı yasalar nedeniyle Almanya’da artık çalışma olanağı kalmayan bilim adamlarından biri de tanınmış genç cerrahi profesörü Rudolf Nissen’dır. Patolog Schwartz ile birlikte Türk Hükümetiyle anlaşmaları imzalayan öncülerden olmuştur. ’da doğan Nissen ’de Münih’te dönemin dünyaca ünlü cerrahı Prof. Dr. Sauerbruch’un yanında asistan, başasistan ve profesör olarak bulunmuştur. ’de dünyada ilk kez pnömonektomiyi başararak şöhretini Almanya dışına da yaymıştır. yılından itibaren, 37 yaşında Ordinaryüs Profesör ünvanıyla İstanbul Üniversitesi Tıp Fakültesi’nin Cerrahpaşa’daki 1. Cerrahi Kliniğine direktör olarak tayin edilmiştir. Cerrahpaşa Cerrahi Kliniğinde çok verimli çalışmalarda bulunmuş, yeni ameliyat teknikleri ve yetiştirdiği cerrahlarla Türk Cerrahisine katkıları büyük olmuştur. Yeni bir cerrahi binasının planlanmasını ve inşaatını sağlamış, Türkçe ve Almanca 4 cerrahi kitabı, 62 Türkçe bilimsel yayın yayımlamıştır. Dünyada ilk kez yaptığı, özellikle akciğer ameliyatlarıyla o dönemde bir efsane olmuştur; örneğin ’da yaptığı bir ameliyat daha sonra Nissen fundoplikasyon işleminin esasını teşkil etmiştir. Rudolf Nissen yılında tedavi amacıyla Amerika Birleşik Devletlerine gitmiş, – yılları arasında Amerika’da kalmış, ’de İsviçre’de Basel Cerrahi Kliniği direktörü olmuştur. yılında emekli olan Prof. Dr. Rudolf Nissen ’de Basel’de vefat etmiştir. Almanya’da göç eden bilim adamları içinde ilk kez anılarını yayınlayan Nissen olmuştur. ’da yayınlanan anılarında Türkiye’deki yaşamını, ülkedeki şartları, gezilerini ve ayrılışını etraflıca yazmıştır (Helle Blaetter, dunkle Blaetter. Erinnerungen eines Chirurgen. Stutgart ). Ülkemizde hâlâ şöhreti devam etmekte olup minnetle hatırlanmaktadır. The University Reform was one of the advancements that the Republic showed with the targets set by Atatürk. In , the will of building a new Turkey and the negative condition of the times resulted in positive outcomes. Rudolf Nissen was one of the young not able to stay in Germany because of the negative working conditions brought about by the Nazis. He was one of the scientists that had foreseen the negative working conditions before they were implemented and had left. He, together with pathologist Schwartz, was one of the first to sign an agreement with the Turkish Government. Nissen was born in , and in he became an assistant to the world famous surgeon seafoodplus.inforuch in Munich; he later became head assistant and professor. In , he successfully completed the pneumonectomy and his fame spread throughout the world. In , he was appointed to the Directorship of Istanbul University Medical Faculty’s Cerrahpaşa 1 st Surgery Clinic at the age of 37 as a Ordinarius Professor. He made many productive Works as the head of the Surgical Clinic, and with the new operating techniques and the surgeons he trained made great contributions to Turkish surgery. Based on his efforts a new surgery building was planned and built. He wrote 4 Turkish and German surgical books and 62 Turkish scientific publications. He became a legend with his surgical operations, especially lung operations; for example, the operation he performed in was the basis for the Nissen fundoplication. One of the great surgeons of the 20th century, Nissen went to the United States in and stayed there between , working around Boston and New York. He became the head of the Basel Surgery Clinic in Switzerland in He retired in Basel in and passed away in Nissen was the first from those who had left Germany to publish his memoirs. His fame continues in our country and he is remembered with admiration.

Darülfünun Tıp Fakültesi 1. Seririyat-ı Hariciye’den İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Genel Cerrahi Anabilim Dalı’na: Kuruluşunun Yılı (–) [ From 1st Surgical Clinic (1. Seririyat-i Hariciye) to Istanbul more

Darülfünun Tıp Fakültesi 1. Seririyat-ı Hariciye’den İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Genel Cerrahi Anabilim Dalı’na: Kuruluşunun Yılı (–) [ From 1st Surgical Clinic (1. Seririyat-i Hariciye) to Istanbul University Cerrahpasa Medical Faculty Department of General Surgery: Celebration of th Year of Foundation () ]

Reactive oxygen species have a known potent role in the pathogenesis of ulcerative colitis. Iloprost, a pharmaceutical, is a chemically stable derivative of a naturally- occurring human prostacyclin. Several studies have demonstrated more

Reactive oxygen species have a known potent role in the pathogenesis of ulcerative colitis. Iloprost, a pharmaceutical, is a chemically stable derivative of a naturally- occurring human prostacyclin. Several studies have demonstrated protective effects of iloprost via its antioxidant and its anti-inflammatory activity. The aim of this study is to evaluate the effects of iloprost on oxidant/antioxidant status, as well as the large bowel histopathology in experimental colitis. Forty adult male Wistar-albino rats were randomly divided in to four equal weight-matched groups: sham group (n=10), iloprost administered sham group (n=10), colitis group (n=10), iloprost administered colitis group (n=10). Acetic acid (1 ml of 4% solution) was used to induce colonic inflammation in the rats. Colonic tissue and plasma malondialdehyde levels were significantly lower in the iloprost administered colitis group than the colitis group (p<). Tissue glutathione levels of the iloprost administere

Ülkemizdeki cerrahi eğitimi ve bilimine bir asırdır hizmet eden Anabilim Dalımız Kuruluşunun + Yılını bilimsel-Cerrahpaşa Cerrahi Toplantıları-, + Yıl Cerrahi Açılış Dersi, resim, karikatür ve heykel sergileri-Sanat more

Ülkemizdeki cerrahi eğitimi ve bilimine bir asırdır hizmet eden Anabilim Dalımız Kuruluşunun + Yılını bilimsel-Cerrahpaşa Cerrahi Toplantıları-, + Yıl Cerrahi Açılış Dersi, resim, karikatür ve heykel sergileri-Sanat Etkinlikleri-ve + Yıl Cerrahpaşa Cerrahi Gecesi şeklinde toplantılarla kutlamıştır. yılında da bilimsel özellikli Cerrahpaşa Cerrahi Toplantıları olarak kutlamaya devam edecektir.

Hydatid disease is a parasitic infection caused by Echinococcus granulosus, and the most frequently affected organ is the liver. Diagnosis is usually based on radiological and serological findings. Even though percutaneous drainage and more

Hydatid disease is a parasitic infection caused by Echinococcus granulosus, and the most frequently affected organ is the liver. Diagnosis is usually based on radiological and serological findings. Even though percutaneous drainage and medical therapies are suggested for selected cases, for the most part surgery is required. The surgical strategy consists of killing the cyst, removing its contagious elements from the liver, obliterating the cystic cavity, and preventing recurrence and complications. A large spectrum of operations - from simple drainage to liver transplantation - has been proposed for reaching these objectives. Laparoscopic surgery is used increasingly for hydatid disease. This article reviews the current status of hydatid disease surgery, with special emphasis on liver cysts.

Between and a total of 38 patients were treated for primary peritoneal tuberculosis in the medical faculty Cerrapaşah, University of Istanbul. Ten patients were operated on as emergency cases because of bowel obstruction, the more

Between and a total of 38 patients were treated for primary peritoneal tuberculosis in the medical faculty Cerrapaşah, University of Istanbul. Ten patients were operated on as emergency cases because of bowel obstruction, the remaining 28 had elective procedures. Seven patients had a diagnosis made laparoscopically, 31 with a laparotomy. In the latter group 13 patients underwent a laparotomy with biopsy without any morbidity or mortality. On the other hand there was no morbidity or mortality after laparoscopic diagnosis and these patients had an average admission time of days. The morbidity and mortality rates of the entire laparotomy group were and % respectively. And the average length of admission was days. In view of our results we would favour laparoscopy as the best diagnostic method for intraabdominal tuberculosis in patients with unspecific abdominal pain and no endoscopically proven cause.

Hydatid disease is a parasitic infection caused by Echinococcus granulosus, and the most frequently affected organ is the liver. Diagnosis is usually based on radiological and serological findings. Even though percutaneous drainage and more

Hydatid disease is a parasitic infection caused by Echinococcus granulosus, and the most frequently affected organ is the liver. Diagnosis is usually based on radiological and serological findings. Even though percutaneous drainage and medical therapies are suggested for selected cases, for the most part surgery is required. The surgical strategy consists of killing the cyst, removing its contagious elements from the liver, obliterating the cystic cavity, and preventing recurrence and complications. A large spectrum of operations - from simple drainage to liver transplantation - has been proposed for reaching these objectives. Laparoscopic surgery is used increasingly for hydatid disease. This article reviews the current status of hydatid disease surgery, with special emphasis on liver cysts.

Notwithstanding the significant advantages compared to open surgery, laparoscopic surgery was considered to be contraindicated in pregnant patients. Currently, there are opposing views on the safety of laparoscopic surgery during more

Notwithstanding the significant advantages compared to open surgery, laparoscopic surgery was considered to be contraindicated in pregnant patients. Currently, there are opposing views on the safety of laparoscopic surgery during pregnancy, especially in last trimester. The aim of this study was to examine feasibility of laparoscopic surgery in pregnant women with acute abdomen. We retrospectively reviewed records of all patients who were admitted to the Emergency Department of Cerrahpasa Medical Faculty between January and January All clinical data of pregnant patient who underwent laparoscopic surgery were analyzed including inpatient records, operative reports, pathology records, and delivery information. Fourteen pregnant patients (mean gestational age weeks, ranged from 9 to 33 weeks) who underwent laparoscopy for appendectomy (n=11), cholecystectomy (n=2), and diagnostic reasons (n=1) were included. Average time of delivery was gestational weeks (range

Abstract In the present study, we aim to share our clinical experience in patients with spontaneous splenic rupture. Splenic rupture without trauma is known as spontaneous splenic rupture. The major problems in the management of more

Abstract In the present study, we aim to share our clinical experience in patients with spontaneous splenic rupture. Splenic rupture without trauma is known as spontaneous splenic rupture. The major problems in the management of spontaneous splenic rupture are missed or delayed diagnosis due to the lack of trauma in most cases. The records of all patients, who were admitted to Cerrahpaşa Medical Faculty, Istanbul University, were retrospectively reviewed from January to March Twelve patients were admitted to the emergency department and they were diagnosed with spontaneous splenic rupture. The mean age was years. All patients had complaints of abdominal pain. The mean hematocrit value was 22%. Radiologic assessment revealed hemoperitoneum and/or subcapsular hematoma in 8 patients while splenic abscess was diagnosed in 2 patients. Eleven patients underwent splenectomy whereas one was managed conservatively. The most common cause of spontaneous splenic rupture was determined to be use of anticoagulants. Etiology was considered to be idiopathic in 1 patient. Two patients died in the postoperative period. Although rare, spontaneous splenic rupture must be suspected in emergency patients who have used especially anticoagulants and antiaggregants and who have had no recent history of trauma. One of the important causes of mortality is missed or delayed diagnosis.

Hepatic hydatid disease is still a commonly seen problem in endemic areas as well as in our country. There is a wide spectrum of therapeutic modalities ranging from simple medical treatment to radical liver resection. Progress in more

Hepatic hydatid disease is still a commonly seen problem in endemic areas as well as in our country. There is a wide spectrum of therapeutic modalities ranging from simple medical treatment to radical liver resection. Progress in laparoscopic procedures made it possible to consider laparoscopic approaches in selected patients with hepatic hydatid disease. The current laparoscopic approach seems to be limited to cystotomy and drainage. There are fewer reports on hepatic resections or pericystectomy in the literature. In this article we present a case of laparoscopic pericystectomy performed in a selected patient.