melike karabacak / Avukat Hakan Karabacak, юридические услуги, Денизли, Меркезефенди, улица Салтак, 48 — Яндекс Карты

Melike Karabacak

melike karabacak

ID: covidwho-1590287


Реферат

OBJECTIVES: This descriptive study aimed to compare the clinical and laboratory features of the children with the multisystem inflammatory syndrome in children (MIS-C), requiring pediatric intensive care unit (PICU), admission with the MIS-C patients who did not require PICU admission. PATIENTS AND METHODS: This study was conducted between March 2020 and February 2021 at the University of Health Sciences Dr. Behçet Uz Children's Hospital, a referral center for pediatric infectious diseases in the Aegean Region of Turkey. All hospitalized patients aged 18 years old or less with MIS-C according to the definition of the universal guidelines were included in the study. Data of the patients with the diagnosis of MIS-C were recorded and collected from the electronic medical records of the hospital. The data included demographic characteristics, presenting signs and symptoms, laboratory findings and clinical data. RESULTS: A total of 58 patients with MIS-C were included in this study. Thirty-eight (65.5%) patients were male. The median age was 6 years (2 months-16 years). The patients admitted to PICU were 15 (25.9%). The rate of pulmonary involvement was 81.3% (n = 13) in the PICU group. The median procalcitonin, C-reactive protein, erythrocyte sedimentation rate, D-Dimer and ferritin values were significantly higher in the PICU group compared to non-PICU group (p < 0.001, p = 0.02, p < 0.001, p = 0.006 and p = 0.031). CONCLUSIONS: Besides the depressing cardiac functions reported before, the pulmonary involvement and signs of shock are important factors for PICU admission in children with MIS-C.


Тема - темы
SARS-CoV-2 , Systemic Inflammatory Response Syndrome , Adolescent , COVID-19/complications , Child , Hospitals, Pediatric , Humans , Intensive Care Units, Pediatric , Male , Retrospective Studies

15.

Evaluation of predictors of severe-moderate COVID-19 infections at children: A review of 292 children.

Kara, Aybüke A; Böncüoglu, Elif; Kiymet, Elif; Arikan, Kamile Ö; Sahinkaya, Sahika; Düzgöl, Mine; Cem, Ela; Çelebi, MIray; Agin, Hasan; Bayram, Süleyman N; Özkan, Behzat; Devrim, Ilker.

J Med Virol ; 93(12): 6634-6640, 2021 Dec.

Статья в английский ID: covidwho-1620151


Реферат

There are two major pandemics in the new millennium, including the pandemic of swine influenza and the COVID-19 pandemic. These two pandemics affected children as well as the adult population. In this case-control study, we compared children with COVID-19 infection and those with H1N1pdm09 virus infection. We also compared the demographic factors, underlying disease, and the requirement for intensive care admission between the hospitalized children with COVID-19 infection and children with H1N1pdm09 virus infection who were hospitalized during the 2009 H1N1 pandemic. In this study, we evaluated 103 patients with H1N1pdm09 virus infection and 392 patients with COVID-19 infection. The age was significantly higher in the COVID-19 patients' group compared to the pandemic influenza group (p < 0.001). The ratio of the children ≥12 years was 10.7% (n = 11) in the H1N1pdm09 virus infection and 36.2% (n = 142) in the COVID-19 group. The rate of underlying disease was significantly higher in the patients with H1N1pdm09 virus infections (p = 0.02). The prevalence of underlying disease in patients requiring PICU hospitalization was 69.2% (n = 9/13) compared to 25.7% (n = 124/482) in patients who did not require PICU hospitalization. The rate of underlying disease was significantly higher in the PICU group regardless of COVID-19 or H1N1pdm09 virus (p = 0.002). Our results suggest that older children were more hospitalized for COVID-19 infections compared to pandemic influenza. In addition, regardless of the type of pandemic infection, the underlying disease is an important factor for pediatric intensive care unit admission. This finding is important for developing strategies for the protection of children with the underlying disease in the upcoming pandemics.


Тема - темы
COVID-19 , Influenza A Virus, H1N1 Subtype , Influenza, Human , Orthomyxoviridae Infections , Adolescent , COVID-19/epidemiology , Case-Control Studies , Child , Hospitalization , Humans , Influenza, Human/epidemiology , Orthomyxoviridae Infections/epidemiology , Pandemics

13.

Evaluation of childhood hospitalization rates and degree of severity of SARS-CoV-2 variants, including B.1.1.7 (Alpha), B.1.315/P.1 (Beta/Gamma), and B.1.617.2 (Delta).

Yilmaz Çelebi, Miray; Kiymet, Elif; Böncüoglu, Elif; Sahinkaya, Sahika; Cem, Ela; Düzgöl, Mine; Akaslan Kara, Aybüke; Ayhan, Fahri Y; Bayram, Süleyman N; Devrim, Ilker.

J Med Virol ; 94(5): 2050-2054, 2022 05.

Статья в английский ID: covidwho-1616024


Реферат

Severe acute respiratory syndrome coronavirus 2 is reappearing with an increasing number of variants every day; this study aimed to determine the effect of B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma), and B.1.617.2 (Delta) variants on hospitalization rates. This single-center study was conducted at the University of Health Sciences Dr. Behçet Uz Children's Hospital from March 11 to August 27, 2021. Variant analyses of symptomatic patients admitted to the hospital who were found to be positive for COVID 19 PCR was performed. Out of 680 cases, 329 (48.4%) were B.1.1.7 variant, 17 (2.5%) were B.1.351/P.1 variant, and 165 (24.2%) were B.1.617.2 variant. One hundred and sixty-nine (24.9%) case variant analysis results were negative. The hospitalization rate of patients with the B.1.617.2 variant was 19.4%, the B.1.351/P.1 variant was 18%, the B.1.1.7 variant was 9.4%, and the negative variant was 10.1%. The B.1.617.2 (Delta) variant, which has become widespread all over the world recently, increases the rate of hospitalization in children.


Тема - темы
COVID-19 , SARS-CoV-2 , COVID-19/epidemiology , Child , Hospitalization , Hospitals, Pediatric , Humans , SARS-CoV-2/genetics

14.

A Comparative Study of Children with MIS-C between Admitted to the Pediatric Intensive Care Unit and Pediatric Ward: A One-Year Retrospective Study.

Kiymet, Elif; Böncüoglu, Elif; Sahinkaya, Sahika; Cem, Ela; Çelebi, Miray Yilmaz; Düzgöl, Mine; Kara, Aybüke Akaslan; Arikan, Kamile Ötiken; Vuran, Gamze Talay; Yilmazer, Murat Muhtar; Sandal, Özlem Saraç; Agin, Hasan; Pirinç, Neslihan; Bayram, Nuri; Devrim, Ilker.

J Trop Pediatr ; 67(6)2021 Dec 08.

Статья в английский ID: covidwho-1943231


Реферат

BACKGROUND: There are limited numbers of studies focusing on renal effects of coronavirus disease 2019 (COVID-19) infection and proximal tubular dysfunction in children with COVID-19 infections. The purpose of this study was to evaluate the functions of the proximal tubule in hospitalized children with confirmed acute COVID-19. METHODS: The children who were hospitalized for confirmed COVID-19 were included in this prospective descriptive analysis. The presence of at least two of the following four abnormalities was used to diagnose proximal tubule injury: abnormal tubular reabsorption of phosphate, normoglycemic glycosuria, hyperuricosuria, and proteinuria. RESULTS: A total of 115 patients were included in the study. About a third of the individuals had elevated blood creatinine levels or proteinuria. In addition, abnormal renal tubular phosphate loss measured by renal tubular phosphate loss was found in 10 (8.7%) patients, as was hyperuricosuria in 28.6%. As a result, total proximal tubular dysfunction was found in 24 (20.9%) patients. CONCLUSIONS: One in every five children with acute COVID-19 infections had proximal tubular dysfunction, according to our data. Although, the rate of proximal tubular dysfunction was lower than in adults, it should be noted. The recovery of proximal tubular function in children with COVID-19 should be followed.


Тема - темы
COVID-19 , Adult , Child , Humans , Phosphates , Prospective Studies , Proteinuria

10.

Prevalence of Anosmia in 10.157 Pediatric COVID-19 Cases: Multicenter Study from Turkey.

Elvan-Tuz, Aysegul; Karadag-Oncel, Eda; Kiran, Sibel; Kanik-Yuksek, Saliha; Gulhan, Belgin; Hacimustafaoglu, Mustafa; Ozdem-Alatas, Silem; Kuyucu, Necdet; Ozdemir, Halil; Egil, Oguz; Elmas-Bozdemir, Sefika; Polat, Meltem; Bursal-Duramaz, Burcu; Cem, Ela; Apaydin, Gozde; Teksam, Ozlem.

Pediatr Infect Dis J ; 41(6): 473-477, 2022 06 01.

Статья в английский

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