Vitamin B12 binds to the intrinsic factor and the combined complex is necessary for absorption across the small intestine mucosa. By contrast, the ossifying fibrous epulis and the giant cell epulis are more prone to recur. It discusses their causes and the underlying mechanisms, and describes how changes in the structure and function of oral tissues relate to clinical presentation. Atlas of Oral Pathology [1 ed. Very rarely, pyostomatitis gangrenosum has been reported as an oral manifestation of ulcerative colitis.
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