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Future studies will address the trans-infection mechanism and whether the virus is simply attached and stabilized at cell surfaces by CLRs or internalized in dedicated compartment awaiting trans-infective release. Moreover, considering the role of CLRs in immunomodulation, their early involvement opens avenues for understanding the imbalanced innate immune response observed in COVID pathogenesis. Ver el apartado Koumpa, F. Pattern Recognition Receptors and Inflammation.
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